Publication: Mefloquine-pyrimethamine-sulfadoxine combination delays emergence of mefloquine resistant Plasmodium falciparum in continuous culture
| dc.contributor.author | P. Tan-Ariya | en_US |
| dc.contributor.author | C. R. Brockelman | en_US |
| dc.contributor.author | C. Menabandhu | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-10-12T07:41:58Z | |
| dc.date.available | 2018-10-12T07:41:58Z | |
| dc.date.issued | 1984-12-01 | en_US |
| dc.description.abstract | The efficacy of mefloquine against Plasmodium falciparum in continuous culture was studied. The development of mefloquine resistance in P. falciparum was significantly inhibited by a combination of mefloquine, pyrimethamine and sulfadoxine. By contrast, more resistant variants were selected in continuous culture without drug pressure or with pyrimethamine-sulfadoxine pressure. The most mefloquine resistant variants were selected by step-wise increases in mefloquine pressure. | en_US |
| dc.identifier.citation | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.15, No.4 (1984), 531-535 | en_US |
| dc.identifier.issn | 00383619 | en_US |
| dc.identifier.other | 2-s2.0-0021591129 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/30627 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021591129&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Mefloquine-pyrimethamine-sulfadoxine combination delays emergence of mefloquine resistant Plasmodium falciparum in continuous culture | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021591129&origin=inward | en_US |