Publication: Structure-activity relationships of dengue antiviral polycyclic quinones
| dc.contributor.author | Dominique Laurent | en_US |
| dc.contributor.author | Francine Baumann | en_US |
| dc.contributor.author | Anne Gaelle Benoit | en_US |
| dc.contributor.author | Alain Mortelecqe | en_US |
| dc.contributor.author | Narong Nitatpattana | en_US |
| dc.contributor.author | Isabelle Desvignes | en_US |
| dc.contributor.author | Cécile Debitus | en_US |
| dc.contributor.author | Manola Laille | en_US |
| dc.contributor.author | Jean Paul Gonzalez | en_US |
| dc.contributor.author | Eliane Chungue | en_US |
| dc.contributor.other | Institut de Recherche pour le Developpement Noumea | en_US |
| dc.contributor.other | Institut Pasteur de Nouvelle-Caledonie Noumea | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Universite de la Nouvelle-Caledonie | en_US |
| dc.contributor.other | Universite Paul Sabatier Toulouse III | en_US |
| dc.date.accessioned | 2018-06-21T08:26:29Z | |
| dc.date.available | 2018-06-21T08:26:29Z | |
| dc.date.issued | 2005-07-01 | en_US |
| dc.description.abstract | The virucidal and antiviral photoactivities of three compounds, hypericin, tetrabromohypericin and gymnochrome B, were evaluated against dengue viruses. All the three products were active, and both the virucidal and antiviral activities were enhanced by light. Gymnochrome B was more potent than hypericin and tetrabromohypericin. The presence of the side chains on the hypericin core of gymnochromes appears to be beneficial for both virucidal and antiviral activities. This enhanced activity is likely to be linked to a complementary mechanism independent of photoactivation. | en_US |
| dc.identifier.citation | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.36, No.4 (2005), 901-905 | en_US |
| dc.identifier.issn | 01251562 | en_US |
| dc.identifier.other | 2-s2.0-27744551966 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/16939 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=27744551966&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Structure-activity relationships of dengue antiviral polycyclic quinones | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=27744551966&origin=inward | en_US |