Publication: CandiVF - Candida albicans virulence factor database
Issued Date
2005-12-01
Resource Type
ISSN
15733904
15733149
15733149
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2-s2.0-28844432624
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Peptide Research and Therapeutics. Vol.11, No.4 (2005), 271-277
Suggested Citation
Songsak Tongchusak, Sansanee C. Chaiyaroj, Anitha Veeramani, Judice L Y Koh, Vladimir Brusic CandiVF - Candida albicans virulence factor database. International Journal of Peptide Research and Therapeutics. Vol.11, No.4 (2005), 271-277. doi:10.1007/s10989-005-9268-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16264
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Title
CandiVF - Candida albicans virulence factor database
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Abstract
Candida albicans is a pathogen commonly infecting patients who receive immunosuppressive drug therapy, long-term catheterization, or those who suffer from acquired immune deficiency syndrome (AIDS). The major factor accountable for pathogenicity of C. albicans is host immune status. Various virulence molecules, or factors, of are also responsible for the disease progression. Virulence proteins are published in public databases but they normally lack detailed functional annotations. We have developed CandiVF, a specialized database of C. albicans virulence factors (http://antigen.i2r.a-star.edu.sg/ Templar/DB/CandiVF/) to facilitate efficient extraction and analysis of data aimed to assist research on immune responses, pathogenesis, prevention, and control of candidiasis. CandiVF contains a large number of annotated virulence proteins, including secretory, cell wall-associated, membrane, cytoplasmic, and nuclear proteins. This database has in-built bioinformatics tools including keyword and BLAST search, visualization of 3D-structures, HLA-DR epitope prediction, virulence descriptors, and virulence factors ontology. © 2005 Springer Science+Business Media, Inc.