Publication: Severe orthostatic hypotension in otherwise uncomplicated Plasmodium vivax infection
Issued Date
2021-12-01
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ISSN
14752875
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2-s2.0-85098855695
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Mahidol University
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SCOPUS
Bibliographic Citation
Malaria Journal. Vol.20, No.1 (2021)
Suggested Citation
Chaisith Sivakorn, Polrat Wilairatana, Srivicha Krudsood, Marcus J. Schultz, Tachpon Techarang, Khanittha Kheawsawaung, Arjen M. Dondorp Severe orthostatic hypotension in otherwise uncomplicated Plasmodium vivax infection. Malaria Journal. Vol.20, No.1 (2021). doi:10.1186/s12936-020-03564-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/77190
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Title
Severe orthostatic hypotension in otherwise uncomplicated Plasmodium vivax infection
Abstract
Impaired autonomic control of postural homeostasis resulting in orthostatic hypotension has been described in falciparum malaria. However, severe orthostatic intolerance in Plasmodium vivax has been rarely reported. A case of non-immune previously healthy Thai woman presenting with P. vivax infection with well-documented orthostatic hypotension is described. In addition to oral chloroquine and intravenous artesunate, the patient was treated with fluid resuscitation and norepinephrine. During hospitalization, her haemodynamic profile revealed orthostatic hypotension persisting for another three days after microscopic and polymerase chain reaction confirmed parasite clearance. Potential causes are discussed.