Publication: Risk of coronary artery disease in patients with systemic sclerosis: A systematic review and meta-analysis
Issued Date
2014-01-01
Resource Type
ISSN
14349949
07703198
07703198
Other identifier(s)
2-s2.0-84904425876
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical Rheumatology. Vol.33, No.8 (2014), 1099-1104
Suggested Citation
Patompong Ungprasert, Prangthip Charoenpong, Praveen Ratanasrimetha, Charat Thongprayoon, Wisit Cheungpasitporn, Promporn Suksaranjit Risk of coronary artery disease in patients with systemic sclerosis: A systematic review and meta-analysis. Clinical Rheumatology. Vol.33, No.8 (2014), 1099-1104. doi:10.1007/s10067-014-2681-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34742
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Risk of coronary artery disease in patients with systemic sclerosis: A systematic review and meta-analysis
Abstract
Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, have been shown to increase coronary artery disease (CAD) risk but the data on systemic sclerosis (SSc) is unclear. We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio, or standardized incidence ratio comparing CAD risk in patients with SSc versus non-SSc participants. Pooled risk ratio and 95 % confidence intervals were calculated using a random effect, generic inverse variance method. Four studies were identified and included in our data analysis. The pooled risk ratio of CAD in patients with SSc was 1.82 (95 % CI, 1.40 to 2.36). The statistical heterogeneity of this meta-analysis was moderate with an I2of 73 %. Our study demonstrated a statistically significant increased CAD risk among patients with SSc. © 2014 Clinical Rheumatology.