Publication: Childhood onset myasthenia gravis
Issued Date
2002-08-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-0036702885
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.85, No.SUPPL. 2 (2002)
Suggested Citation
Natte Raksadawan, Kampanad Balankura, Tumtip Sangruchi, Pongkiat Kankirawatana, Patcharin Prateepratana, L. A Ongsri Atchaneeyasakul Childhood onset myasthenia gravis. Journal of the Medical Association of Thailand. Vol.85, No.SUPPL. 2 (2002). Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20440
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Childhood onset myasthenia gravis
Other Contributor(s)
Abstract
The authors share experiences in taking care of 27 cases of childhood onset myasthenia gravis (MGS). In all cases, the diagnosis was confirmed by a combination of clinical examination and Neostigmine test. The majority (92%) had localized ocular myasthenia with median onset of symptoms at 33 months of age. About 24 per cent of them progressed to generalized MGS. A few (8%) presented with respiratory failure that required ventilatory support with onset of symptoms at about 22 months. Thymectomy was performed in 10 cases. Complete and partial remissions were achieved in about 70 per cent and 26 per cent of cases respectively with the combination of an immunosuppressant (azathioprine) and a Cholinesterase inhibitor (pyridostigmine). None experienced a myasthenic crisis with proper management and good follow-up using the above combinations.