Publication:
Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines

Issued Date

2017-01-01

Resource Type

Article

ISSN

14770520

DOI

10.1039/c7ob00776k

Other identifier(s)

2-s2.0-85021655912

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Organic and Biomolecular Chemistry. Vol.15, No.20 (2017), 4320-4327

Suggested Citation

Chaleena Pimpasri, Ladawan Sumunnee, Sirilata Yotphan Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines. Organic and Biomolecular Chemistry. Vol.15, No.20 (2017), 4320-4327. doi:10.1039/c7ob00776k Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42052

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Title

Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines

Author(s)

Chaleena Pimpasri
 Ladawan Sumunnee
 Sirilata Yotphan

Other Contributor(s)

Mahidol University

Abstract

© 2017 The Royal Society of Chemistry. A copper-catalyzed oxidative decarboxylative coupling of α-keto acids with NH-sulfoximines has been developed. With CuBr as the catalyst and K2S2O8as the oxidant, this reaction enables the formation of a C-N bond and gives N-aroylsulfoximine products in moderate to excellent yields. The reaction mechanism is likely to involve the generation of a reactive aroyl radical intermediate.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/42052

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Scopus 2016-2017