Publication: Malaria: What's New in the Management of Malaria?
Issued Date
2019-03-01
Resource Type
ISSN
15579824
08915520
08915520
Other identifier(s)
2-s2.0-85060874108
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Infectious Disease Clinics of North America. Vol.33, No.1 (2019), 39-60
Suggested Citation
Katherine Plewes, Stije J. Leopold, Hugh W.F. Kingston, Arjen M. Dondorp Malaria: What's New in the Management of Malaria?. Infectious Disease Clinics of North America. Vol.33, No.1 (2019), 39-60. doi:10.1016/j.idc.2018.10.002 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51835
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Malaria: What's New in the Management of Malaria?
Other Contributor(s)
Abstract
© 2018 Elsevier Inc. The global burden of malaria remains high, with 216 million cases causing 445,000 deaths in 2016 despite first-line treatment with artemisinin-based combination therapy. Decreasing transmission in Africa shifts the risk for severe malaria to older age groups as premunition wanes. Prompt diagnosis and treatment with intravenous artesunate in addition to appropriate supportive management are critical to reduce deaths from severe malaria. Effective individual management is challenging in settings with limited resources for higher-level care. Adjunctive therapies targeting the underlying pathophysiological pathways have the potential to reduce mortality. Resistance to artemisinin derivatives and their partner drugs threaten malaria management and control.