Publication: Pathophysiology of malaria
Issued Date
1981-12-01
Resource Type
ISSN
00383619
Other identifier(s)
2-s2.0-0019838802
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.12, No.3 (1981), 298-307
Suggested Citation
T. Chongsuphajaisiddhi Pathophysiology of malaria. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.12, No.3 (1981), 298-307. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/30184
Research Projects
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Journal Issue
Thesis
Title
Pathophysiology of malaria
Author(s)
Other Contributor(s)
Abstract
The pathophysiology of malaria infection is presented from animal studies and the various manifestations occurring in human cases. Maegraith (1974) proposed the concept of a chain reaction of physiological processes that leads to the disease following malarial infection. It may be seen that the malaria parasites first damage the infected red blood cells directly and then initiate a chain reaction of nonspecific inflammatory processes and later on immunological responses aggravating further the inflammatory reactions. Because of the interdependence in nature of these changes as suggested by Maegraith in 1977, it is usually difficult to clearly identify these three mechanisms.