Publication: In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand
| dc.contributor.author | Kesinee Chotivanich | en_US |
| dc.contributor.author | Rachanee Udomsangpetch | en_US |
| dc.contributor.author | Wirongrong Chierakul | en_US |
| dc.contributor.author | Paul N. Newton | en_US |
| dc.contributor.author | Ronatrai Ruangveerayuth | en_US |
| dc.contributor.author | Sasithon Pukrittayakamee | en_US |
| dc.contributor.author | Sornchai Looareesuwan | en_US |
| dc.contributor.author | Nicholas J. White | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Mae Sot General Hospital | en_US |
| dc.contributor.other | Churchill Hospital | en_US |
| dc.date.accessioned | 2018-07-24T03:43:53Z | |
| dc.date.available | 2018-07-24T03:43:53Z | |
| dc.date.issued | 2004-04-01 | en_US |
| dc.description.abstract | The susceptibility of 20 isolates of Plasmodium vivax on the Thailand-Myanmar border to seven antimalarial drugs was evaluated using the schizont maturation inhibition technique. The geometric mean 50% inhibition concentration (IC50) values were quinine = 308 ng/mL, amodiaquine = 14 ng/mL, chloroquine = 50 ng/mL, mefloquine = 127 ng/mL, sulfadoxine/pyrimethamine (80:1) = 800/10 ng/mL, pyrimethamine = 8 ng/mL, and artesunate = 0.5 ng/mL. Compared with P. falciparum in this area, P. vivax was more sensitive to chloroquine and artesunate, equally sensitive to quinine, and more resistant to mefloquine. | en_US |
| dc.identifier.citation | American Journal of Tropical Medicine and Hygiene. Vol.70, No.4 (2004), 395-397 | en_US |
| dc.identifier.issn | 00029637 | en_US |
| dc.identifier.other | 2-s2.0-1942501224 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/21395 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=1942501224&origin=inward | en_US |
| dc.subject | Immunology and Microbiology | en_US |
| dc.subject | Medicine | en_US |
| dc.title | In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=1942501224&origin=inward | en_US |