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Mechanism-Based Design, Synthesis, and in Vitro Antimalarial Testing of New 4-Methylated Trioxanes Structurally Related to Artemisinin: The Importance of a Carbon-Centered Radical for Antimalarial Activity

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Gary H. Posner, Chang Ho Oh, Dasong Wang, Lucia Gerena, Wilbur K. Milhous, Steven R. Meshnick, Wanida Asawamahasadka Mechanism-Based Design, Synthesis, and in Vitro Antimalarial Testing of New 4-Methylated Trioxanes Structurally Related to Artemisinin: The Importance of a Carbon-Centered Radical for Antimalarial Activity. Journal of Medicinal Chemistry. Vol.37, No.9 (1994), 1256-1258. doi:10.1021/jm00035a003 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/9516

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