Publication: Potential factors associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma
Issued Date
2020-03-17
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ISSN
26730871
08576084
08576084
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2-s2.0-85090167293
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Mahidol University
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SCOPUS
Bibliographic Citation
Thai Journal of Obstetrics and Gynaecology. Vol.28, No.2 (2020), 86-93
Suggested Citation
Prakasit Karavanich, Atthapon Jaishuen Potential factors associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma. Thai Journal of Obstetrics and Gynaecology. Vol.28, No.2 (2020), 86-93. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/59233
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Title
Potential factors associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma
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Abstract
© Thai Journal of Obstetrics and Gynaecology 2020. All rights reserved. Objectives: To explore factors that associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma Materials and Methods: Two hundred and ninety-three patients with endometrioid endometrial carcinoma, who received surgical staging in Siriraj Hospital during 2008-2016, were studied. The relationship between pelvic lymph node metastasis and these data: demographic factors, biochemical markers, preoperative and intraoperative tumor characteristics were analysed by using a logistic regression model. Results: From multivariate analysis, associated factors were grade of tumor, platelet count, deep myometrial invasion (deep MI: more than half of myometrial invasion) and size of tumor. Platelet count and size of tumor were re-calculated. Thrombocytosis (platelet count more than or equal to 380,000/mm3) and large tumor (tumor size more than or equal to 6 centimeters) were statistically significant for cut-off point. Conclusion: Grade of tumor, platelet count, more than half of depth of myometrial invasion and size of tumor, were associated with pelvic lymph node metastasis in endometrioid endometrial carcinoma.