Publication: Low hip bone mineral density predicts mortality in maintenance hemodialysis patients: A five-year follow-up study
Issued Date
2014-01-01
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ISSN
14219735
02535068
02535068
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2-s2.0-84893670853
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Mahidol University
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SCOPUS
Bibliographic Citation
Blood Purification. Vol.37, No.1 (2014), 33-38
Suggested Citation
Sinee Disthabanchong, Sutipong Jongjirasiri, Surawat Adirekkiat, Vasant Sumethkul, Atiporn Ingsathit, Somnuek Domrongkitchaiporn, Bunyong Phakdeekitcharoen, Surasak Kantachuvesiri, Chagriya Kitiyakara Low hip bone mineral density predicts mortality in maintenance hemodialysis patients: A five-year follow-up study. Blood Purification. Vol.37, No.1 (2014), 33-38. doi:10.1159/000357639 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34480
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Title
Low hip bone mineral density predicts mortality in maintenance hemodialysis patients: A five-year follow-up study
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Abstract
Background: Bone loss is common among hemodialysis patients and contributes to mortality. The association between bone loss and vascular calcification may explain the increased mortality risk. Studies on the association between decreased bone mass and mortality in maintenance hemodialysis patients are limited. Methods: Eighty-three hemodialysis patients underwent bone mineral density (BMD) and coronary artery calcification (CAC) measurements. The relationship between BMD and mortality was analyzed after a 5-year follow-up period. Results: Eighty percent of the patients had reduced hip BMD. In univariate Cox regression analyses, age, cardiovascular disease, dyslipidemia, increased CAC score, increased comorbidity score and decreased hip BMD were associated with mortality. Low hip BMD remained independently associated with mortality after adjustments for cardiovascular risk factors, comorbidity score and CAC score. Patients with BMD in the lowest tertile had the worst survival. Conclusion: Low hip BMD predicted mortality in maintenance hemodialysis patients independent of CAC. © 2014 S. Karger AG, Basel.