Publication: Plasmodium berghei: Detection in organs of infected mice by means of immuno-fluorescence
Issued Date
1973-01-01
Resource Type
ISSN
00359203
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2-s2.0-0015863609
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Mahidol University
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SCOPUS
Bibliographic Citation
Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.67, No.3 (1973), 410-415
Suggested Citation
Somnate Boonpucknavig, Puangpen Benchachai, Vijitr Boonpucknavig, Natth Bhamarapravati Plasmodium berghei: Detection in organs of infected mice by means of immuno-fluorescence. Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.67, No.3 (1973), 410-415. doi:10.1016/0035-9203(73)90119-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/10133
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Title
Plasmodium berghei: Detection in organs of infected mice by means of immuno-fluorescence
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Abstract
An immunofluorescent study of the malarial antigen in the tissues of mice infected with Plasmodium berghei (berghei strain) was conducted. In the first week of infection, the malarial antigen appears in corpuscular forms in the erythrocytes located in the vessels of the spleen, liver and kidney. From the second week onward, when antibodies to malaria begin to be detected, a new form of the malarial antigen, which appears as coarse granules, is detected in the fixed RE cells of the liver, spleen and in the glomerular endothelial and mesangial cells. There is a progressive decrease in the amount of the corpuscular form of the malarial antigen with a concomitant increase in the granular form. In the third week, most of the malarial antigen in the tissues is granular and the corpuscular form is rarely seen. © 1973.