Publication: Histiocytoid neutrophilic dermatitis, an unusual histopathology in neonatal lupus erythematosus
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Issued Date
2015-12-01
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ISSN
16000560
03036987
03036987
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2-s2.0-84956961375
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Cutaneous Pathology. Vol.42, No.12 (2015), 996-999
Suggested Citation
Panitta Sitthinamsuwan, Rattanavalai Nitiyarom, Manasmon Chairatchaneeboon, Wanee Wisuthsarewong Histiocytoid neutrophilic dermatitis, an unusual histopathology in neonatal lupus erythematosus. Journal of Cutaneous Pathology. Vol.42, No.12 (2015), 996-999. doi:10.1111/cup.12594 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/36228
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Title
Histiocytoid neutrophilic dermatitis, an unusual histopathology in neonatal lupus erythematosus
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Abstract
© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. The authors reported histiocytoid neutrophilic dermatitis in neonatal lupus erythematosus (NLE). One-month-old male infant presented with annular erythematous plaques at the face and trunk. Serologic studies revealed positive anti-ribonuclear protein antibodies (RNP) and antinuclear antibodies (ANA). Histopathology showed predominant myeloid lineage mononuclear cells admixed with segmented neutrophils. This finding is uncommon in cutaneous NLE. Cutaneous NLE and LE should be included in the differential diagnosis of histiocytoid neutrophilic dermatitis. Additional immunohistochemistry studies with clinical and serologic correlations are important to differentiate histiocytoid neutrophilic dermatitis from the other diagnoses, especially leukemic cutis in young patients.