Publication: Ferrokinetics in patients with malaria: Haemoglobin synthesis and normoblasts in vitro
dc.contributor.author | Tanomsri Srichaikul | en_US |
dc.contributor.author | Thitiporn Siriasawakul | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.contributor.other | Chulalongkorn University | en_US |
dc.date.accessioned | 2018-04-19T14:11:59Z | |
dc.date.available | 2018-04-19T14:11:59Z | |
dc.date.issued | 1976-01-01 | en_US |
dc.description.abstract | Bone marrow cultures in 15 Plasmodium falciparum patients were studied both during and after parasitaemia. Abnormalities were observed only in the group during parasitaemia. These abnormalities included: (1) decreased normoblastic number and cellular iron incorporation in all cases; (2) premature death of normoblasts during their development in the cultures in all cases; (3) defective haemoglobin synthesis in 3 of 11 cases (27%). A causal relationship between defective haemoglobin synthesis and degree of normoblastic destruction in the cultures was found. Marked anaemia and depressed C’ 3 level were found only in the group with defective haemoglobin synthesis. The significance of these findings is discussed. © 1976 Oxford University Press. | en_US |
dc.identifier.citation | Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.70, No.3 (1976), 244-246 | en_US |
dc.identifier.doi | 10.1016/0035-9203(76)90048-1 | en_US |
dc.identifier.issn | 18783503 | en_US |
dc.identifier.issn | 00359203 | en_US |
dc.identifier.other | 2-s2.0-0017130386 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/10874 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0017130386&origin=inward | en_US |
dc.subject | Immunology and Microbiology | en_US |
dc.subject | Medicine | en_US |
dc.title | Ferrokinetics in patients with malaria: Haemoglobin synthesis and normoblasts in vitro | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0017130386&origin=inward | en_US |