Publication: A fluctuation of serum osmolality inducing osmotic demyelination syndrome
Issued Date
2010-12-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-79952505143
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.93, No.SUPPL 7 (2010)
Suggested Citation
Sookkasem Khositset, Sugravan Intraka, Wanida Pao-in, Ananit Visudtibha A fluctuation of serum osmolality inducing osmotic demyelination syndrome. Journal of the Medical Association of Thailand. Vol.93, No.SUPPL 7 (2010). Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/29426
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
A fluctuation of serum osmolality inducing osmotic demyelination syndrome
Other Contributor(s)
Abstract
Osmotic demyelination syndrome (ODS) is an uncommon acute demyelinating process which involves the central nervous system. Rapid correction of chronic hyponatremia with increasing serum osmolality is the most common cause of ODS. We report the first case of an infant with moderate dehydration and initially normal serum Na who developed ODS associated with a fluctuation of serum osmolality. We present the lowest decreasing rate of serum Na level ever reported causing ODS. The fluctuation of serum osmolality in this case expands the list of precipitating causes of ODS in children. The case also highlights the appropriate intravenous fluid for initial rehydration in infant.