Publication: Human pathology of Opisthorchis viverrini infection: a comparison of adults and children.
Issued Date
1989-03-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0024625883
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Mahidol University
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SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.20, No.1 (1989), 95-100
Suggested Citation
M. Riganti, S. Pungpak, B. Punpoowong, D. Bunnag, T. Harinasuta Human pathology of Opisthorchis viverrini infection: a comparison of adults and children.. The Southeast Asian journal of tropical medicine and public health. Vol.20, No.1 (1989), 95-100. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15818
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Title
Human pathology of Opisthorchis viverrini infection: a comparison of adults and children.
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Abstract
The pathology of human opisthorchiasis in 22 adults (20 to 68 years) and 7 children (7 to 15 years) at autopsy is described. The changes of the liver in adults and children are similar and are summarized as follows: Enlargement of the liver was a common finding. Pericholangitis was observed in most cases. The pathology was confined to the large and medium-sized bile ducts where the flukes inhabited. The small interlobular bile ducts had minimal or unremarkable changes. Dilatation of the bile ducts with hyperplasia, desquamation and proliferation of the bile duct epithelial cells, glandular formation and fibrous connective tissue infiltration of the walls were the most common features. The pathological changes were well established within 7 to 15 years. Dilatation of the gallbladder, chronic cholecystitis and carcinoma were found only in adults. Eight of ten cases were cholangiocarcinoma and two were hepatocellular carcinoma.