Publication: Generation of a serine/threonine-protein kinase LATS1 gene-edited iPSC MUSIi012-A-3
| dc.contributor.author | Chanchao Lorthongpanich | en_US |
| dc.contributor.author | Chuti Laowtammathron | en_US |
| dc.contributor.author | Nittaya Jiamvoraphong | en_US |
| dc.contributor.author | Pimonwan Srisook | en_US |
| dc.contributor.author | Pimjai Chingsuwanrote | en_US |
| dc.contributor.author | Phatchanat Klaihmon | en_US |
| dc.contributor.author | Supaporn Waeteekul | en_US |
| dc.contributor.author | Yaowalak U-pratya | en_US |
| dc.contributor.author | Surapol Issaragrisil | en_US |
| dc.contributor.other | Faculty of Medicine, Siriraj Hospital, Mahidol University | en_US |
| dc.contributor.other | Wattanosoth Hospital | en_US |
| dc.date.accessioned | 2020-08-25T09:01:00Z | |
| dc.date.available | 2020-08-25T09:01:00Z | |
| dc.date.issued | 2020-10-01 | en_US |
| dc.description.abstract | © 2020 The Authors In mammals, there are a number of kinases, including serine/threonine-protein kinase LATS1, that act as a core kinase of the Hippo pathway and that negatively regulate the Hippo effector protein YAP and its paralog TAZ. Using CRISPR/Cas9 technology, we established a stable LATS1 knockdown (LATS1-KD) iPSC from the MUSIi012-A cell line. The LATS1-KD iPSC MUSIi012-A-3 that was developed maintained both the normal karyotype and the pluripotent phenotype, and retained the ability to differentiate into all three embryonic germ layers. | en_US |
| dc.identifier.citation | Stem Cell Research. Vol.48, (2020) | en_US |
| dc.identifier.doi | 10.1016/j.scr.2020.101950 | en_US |
| dc.identifier.issn | 18767753 | en_US |
| dc.identifier.issn | 18735061 | en_US |
| dc.identifier.other | 2-s2.0-85089190010 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/57672 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85089190010&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.title | Generation of a serine/threonine-protein kinase LATS1 gene-edited iPSC MUSIi012-A-3 | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85089190010&origin=inward | en_US |