Publication: Prolonged QT interval and risk of sudden death in South-East Asian men
Issued Date
1991-08-03
Resource Type
ISSN
01406736
Other identifier(s)
2-s2.0-0025851084
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Lancet. Vol.338, No.8762 (1991), 280-281
Suggested Citation
R. G. Munger, M. P. Jones, R. J. Prineas, R. S. Crow, S. Changbumrung, V. Wangsuphachart, V. Keane Prolonged QT interval and risk of sudden death in South-East Asian men. The Lancet. Vol.338, No.8762 (1991), 280-281. doi:10.1016/0140-6736(91)90419-P Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/22124
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Title
Prolonged QT interval and risk of sudden death in South-East Asian men
Abstract
Sudden death in sleep occurs in substantial numbers among young men in South-East Asia. The frequencies of electrocardiographic abnormalities were measured in groups with varying risks of such sudden death. The mean heart-rate-corrected QT interval (QTc) was significantly (p<0·05) greater among 123 Laotian refugees in Thailand at high risk (405 [95% confidence interval 397-413] ms) than in 77 Laotian refugees in the United States at lower risk (364 [359-369] ms) and 199 non-Asian US residents at negligible risk (358 [354-362] ms). Among refugees in Thailand, prolonged QTc interval was associated with poor thiamine status and a history of seizure-like episodes in sleep. Thiamine deficiency may be a cause of prolonged QT interval and sudden death in this region. © 1991.