Publication:
Thrombopoietin in Plasmodium falciparum malaria

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dc.contributor.authorAnna Kreilen_US
dc.contributor.authorChristoph Wenischen_US
dc.contributor.authorGary Brittenhamen_US
dc.contributor.authorSornchai Looareesuwanen_US
dc.contributor.authorMarkus Peck-Radosavljevicen_US
dc.contributor.otherUniversitat Wienen_US
dc.contributor.otherKarl-Franzens-Universitat Grazen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-09-07T09:23:55Z
dc.date.available2018-09-07T09:23:55Z
dc.date.issued2000-01-01en_US
dc.description.abstractThrombopoietin (TPO) is the key growth factor for platelet production and is elevated in states of platelet depletion. As thrombocytopenia is a common finding in malaria, we analysed TPO regulation before, during and after antimalarial treatment. Before treatment, TPO serum levels were significantly higher in patients with severe malaria (n = 35) than in patients with uncomplicated malaria (n = 44; P = 0.024), normalizing within 14-21 d of therapy. The rapid normalization of TPO levels and increase in low peripheral platelet counts after treatment indicate that the biosynthesis of TPO and its regulation in malaria patients are normal.en_US
dc.identifier.citationBritish Journal of Haematology. Vol.109, No.3 (2000), 534-536en_US
dc.identifier.doi10.1046/j.1365-2141.2000.02096.xen_US
dc.identifier.issn00071048en_US
dc.identifier.other2-s2.0-0034044675en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/26336
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034044675&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleThrombopoietin in Plasmodium falciparum malariaen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034044675&origin=inwarden_US

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