Publication: Development of Electrochemical Electrodes Using Carbon Nanotube and Metal Phthalocyanine to Classify Pharmaceutical Drugs
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Issued Date
2020-01-01
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ISSN
22147853
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2-s2.0-85084445687
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Mahidol University
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SCOPUS
Bibliographic Citation
Materials Today: Proceedings. Vol.23, (2020), 732-737
Suggested Citation
Sarika Pradhan, Arthit Jityen, Theerasak Juagwon, Asawin Sinsarp, Tanakorn Osotchan Development of Electrochemical Electrodes Using Carbon Nanotube and Metal Phthalocyanine to Classify Pharmaceutical Drugs. Materials Today: Proceedings. Vol.23, (2020), 732-737. doi:10.1016/j.matpr.2019.12.266 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/56222
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Title
Development of Electrochemical Electrodes Using Carbon Nanotube and Metal Phthalocyanine to Classify Pharmaceutical Drugs
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Abstract
© 2019 Elsevier Ltd. Electronic tongues are analytical electrochemical technique which mimic human tongue. The taste sensing system like an electronic tongue has been successfully used to distinguish five basic tastes and as quality analysing tool in food and beverages industries. In this study, the chemical electrodes with multiwall carbon nanotube were developed to classify active pharmaceutical ingredients and analyse the capability of sweetener in masking bitterness of these formulation since multiwall carbon nanotube exhibits high electrical conductivity and electrocatalytic behaviour. The electronic tongue system comprises Ag/AgCl as reference electrode, platinum wire as counter electrode and working electrode was modified using four different metal phthalocyanines with multiwall carbon nanotube. The used active metal phthalocyanine powder includes cobalt, iron, zinc and magnesium phthalocyanine. The cyclic voltammogram of various pharmaceutical sample solutions of quinine, amoxicillin, ranitidine and paracetamol were examined between optimized potential range with set constant scan rate. The mapping evaluated from principal component analysis indicated that the metal phthalocyanines mixed with carbon nanotube sensors have potential to classify pharmaceutical drugs. When the pharmaceutical drugs were mixed with sweetener at different concentration, the obtained results indicated that the fabricated working electrode can be used to analyse the suppression of bitterness by sweeteners.