Publication: A retrospective study of multiple sclerosis in Thailand
Issued Date
2010-12-01
Resource Type
ISSN
18236138
Other identifier(s)
2-s2.0-79951808626
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Mahidol University
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SCOPUS
Bibliographic Citation
Neurology Asia. Vol.15, No.3 (2010), 253-261
Suggested Citation
Sasitorn Siritho, Naraporn Prayoonwiwat, Teeratorn Pulkes, Siwaporn Chankrachang, Somsak Laptikultham, Samart Nidhinandana, Suwanna Sethawacharawanit, Tasanee Tantirittisak, Arkhom Arayawichanont A retrospective study of multiple sclerosis in Thailand. Neurology Asia. Vol.15, No.3 (2010), 253-261. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/29438
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Title
A retrospective study of multiple sclerosis in Thailand
Abstract
Objectives: To determine the prevalence of Thai demyelinating diseases regarding demographic data, symptoms and signs, associated diseases, disease progression, cerebrospinal fluid analysis and imaging findings. Methods: A multicenter retrospective study of 107 MS patients attending the Neurological Centers in Thailand during June and December 2004 was performed. Each had an initial diagnosis of demyelinating diseases. Results: From 107 patients, there were 78.5% female and 21.5% male with the female: male ratio of 3.7:1. The age at onset was 32.7±11.5 years. The mean disease duration was 3.8±5.1 years and the mean number of relapses was 4.6±4.4 with annual relapse rate of 1.5±1.3 times. None reported a family history of MS. Recurrent optico-spinal form was 27.1% followed by 17.8% of spinal form and 15% of western form of MS. The most common presenting symptom was visual impairment (51.4%). Only 24.1% demonstrated oligoclonal bands in CSF. The median score of EDSS at their latest visits was 3.0 with mean score of 3.8±3.0. Conclusions: MS in Thailand is different from Western countries. There were no occurrence of MS in families, higher incidence of visual impairment at onset, more common recurrent optico-spinal form and lower incidence of oligoclonal bands in the CSF.