Publication: Osteoblastic functions: A lesson from biochemical bone markers
Issued Date
2011-10-01
Resource Type
ISSN
01252208
Other identifier(s)
2-s2.0-84858057912
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.94, No.10 SUPPL. (2011)
Suggested Citation
Narong Bunyaratavej Osteoblastic functions: A lesson from biochemical bone markers. Journal of the Medical Association of Thailand. Vol.94, No.10 SUPPL. (2011). Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/12286
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Osteoblastic functions: A lesson from biochemical bone markers
Author(s)
Other Contributor(s)
Abstract
The present study showed the lowest values of bone markers from osteoblast, NMID osteocalcin, 10.81 ± 3.9 ng/ml and PINP 15.88 ± 7.09 ng/ml at lowest level of osteoclast, betaCTx, 0.066 ± 0.22 ng/ml should be the cut value for osteoblastic function. At this level betaCTx, had no correlation with PINP (r = 0.198, p = 0.003) or NMID osteocalcin (r =0.035, p = 0.606) compared to the normal value of the control group and the correlation (r) between betaCTx and NMID osteocalcin, betaCTx and PINP, which were 0.757 and 0.752 (p = 0.001) respectively and recognized as normal bone turnover with coupling effect. So, bone markers of osteoblast at the lowest value of betaCTx (0.066 ng/ml) with NMID osteocalcin, 10.81 ± 3.9 ng/ml and PINP 15.887.09 ng/ml may be the cut value of osteoblast reflecting poor functions. The benefit of identifying the cut values of osteoblast will help in making decisions in osteoporotic management.