Publication: Effect of pesticide exposure on immunological, hematological and biochemical parameters in thai orchid farmers— A cross-sectional study
Issued Date
2015-05-27
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ISSN
16604601
16617827
16617827
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2-s2.0-84930672931
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Environmental Research and Public Health. Vol.12, No.6 (2015), 5846-5861
Suggested Citation
Soraya Aroonvilairat, Wannapa Kespichayawattana, Thiwaree Sornprachum, Papada Chaisuriya, Taweeratana Siwadune, Kavi Ratanabanangkoon Effect of pesticide exposure on immunological, hematological and biochemical parameters in thai orchid farmers— A cross-sectional study. International Journal of Environmental Research and Public Health. Vol.12, No.6 (2015), 5846-5861. doi:10.3390/ijerph120605846 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/35993
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Title
Effect of pesticide exposure on immunological, hematological and biochemical parameters in thai orchid farmers— A cross-sectional study
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Abstract
© 2015 by the authors; licensee MDPI, Basel, Switzerland. Various studies have found that many Thai orchid farmers used excessive amounts of pesticides without proper protective gear, but no toxicological study has been made. This cross-sectional study aimed to evaluate the immunological, hematological and biochemical statuses of these farmers. Sixty four orchid farmers and 60 controls were studied. Plasma cholinesterase activity, the percentage and absolute number of B lymphocytes (CD19+) were significantly lower in the farmers group (3966.32 ± 1165.48 U/L, 11.61 ± 4.09% and 312.26 ± 164.83 cells/mm3, respectively) as compared to those of controls (5048.85 ± 1139.40 U/L, 14.32 ± 4.23%, 420.34 ± 195.18 cells/mm3, respectively). There was a statistically significant higher level of serum IgE among the orchid farmers (0.031 ± 0.011 mg/dL vs. 0.018 ± 0.007 mg/dL) but not IgG, IgA and IgM, levels. Serum lysozyme level, lymphocyte proliferative responses to mitogens, hematological parameters and kidney function test, were not significantly different between the two groups. The liver function profiles showed significantly lower levels of albumin and serum protein in the farmer group. Thus frequent pesticide exposure resulted in subtle changes of some biological parameters. These changes, though may not be clinically significant, strongly indicated that caution in handing pesticides by these farmers is warranted.