Publication: Polycyclic polyprenylated acylphloroglucinols and biphenyl derivatives from the roots of Garcinia nuntasaenii Ngerns. & Suddee
Issued Date
2018-02-01
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ISSN
00319422
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2-s2.0-85037845209
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Mahidol University
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SCOPUS
Bibliographic Citation
Phytochemistry. Vol.146, (2018), 63-74
Suggested Citation
Suppisak Chaturonrutsamee, Chutima Kuhakarn, Panida Surawatanawong, Samran Prabpai, Palangpon Kongsaeree, Thaworn Jaipetch, Pawinee Piyachaturawat, Surawat Jariyawat, Radeekorn Akkarawongsapat, Kanoknetr Suksen, Jitra Limthongkul, Chanita Napaswad, Narong Nuntasaen, Vichai Reutrakul Polycyclic polyprenylated acylphloroglucinols and biphenyl derivatives from the roots of Garcinia nuntasaenii Ngerns. & Suddee. Phytochemistry. Vol.146, (2018), 63-74. doi:10.1016/j.phytochem.2017.12.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/44824
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Title
Polycyclic polyprenylated acylphloroglucinols and biphenyl derivatives from the roots of Garcinia nuntasaenii Ngerns. & Suddee
Abstract
© 2017 Elsevier Ltd Seven previously undescribed compounds, including three polycyclic polyprenylated acylphloroglucinols (garcinuntins A–C), three biphenyl derivatives (garcinuntabiphenyls A–C) and a lanostane triterpene (garcinuntine), along with thirteen known compounds were isolated from the root of Garcinia nuntasaenii Ngerns. & Suddee. Their structures were elucidated on the basis of spectroscopic techniques. For garcinuntins A–C, the absolute configurations were confirmed by the combination of single X-ray crystallography and ECD calculations. Anti-HIV activity using anti-HIV-1 reverse transcriptase and syncytium inhibition assays, and cytotoxic activity against a panel of cultured mammalian cancer cell lines of isolated compounds were investigated.