Publication: Immunodiagnosis of human trichinellosis and identification of specific antigen for Trichinella spiralis
Issued Date
1995-01-01
Resource Type
ISSN
00207519
Other identifier(s)
2-s2.0-0028831072
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal for Parasitology. Vol.25, No.1 (1995), 87-94
Suggested Citation
Pakpimol Mahannop, Prasert Setasuban, Nimit Morakote, Pramuan Tapchaisri, Wanpen Chaicumpa Immunodiagnosis of human trichinellosis and identification of specific antigen for Trichinella spiralis. International Journal for Parasitology. Vol.25, No.1 (1995), 87-94. doi:10.1016/0020-7519(94)E0024-H Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/17306
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Title
Immunodiagnosis of human trichinellosis and identification of specific antigen for Trichinella spiralis
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Abstract
Crude antigens obtained from the infective stage larvae of Trichinella spiralis were used in an ELISA for detecting IgG antibodies to T. spiralis in serum samples collected from three groups of individuals. The individuals of the first group were parasitologically confirmed trichinellosis patients, while those of group 2 were patients with other helminthiasis and group 3 were healthy, parasite-free individuals. The specificity of the assay was 96.8% when performed on sera of groups 2 and 3. Cross-reaction was observed with the sera of patients with capillariasis, gnathostomiasis, opisthorchiasis, and strongyloidiasis and opisthorchiasis with hookworm infection. The sensitivity of the test was 100% when performed on sera of group 1, which were collected 57 days after infection. Western blot analysis revealed that a specific antigen for T. spiralis was a component of Mr109. © 1995.