Publication: Glioblastoma multiforme at the corpus callosum with spinal leptomeningeal metastasis
Issued Date
2011-06-01
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ISSN
03038467
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2-s2.0-79955833886
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Mahidol University
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SCOPUS
Bibliographic Citation
Clinical Neurology and Neurosurgery. Vol.113, No.5 (2011), 407-410
Suggested Citation
Pirada Witoonpanich, Krittika Bamrungrak, Artit Jinawath, Sansanee Wongwaisayawan, Suchart Phudhichareonrat, Rawiphan Witoonpanich Glioblastoma multiforme at the corpus callosum with spinal leptomeningeal metastasis. Clinical Neurology and Neurosurgery. Vol.113, No.5 (2011), 407-410. doi:10.1016/j.clineuro.2010.12.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/12479
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Title
Glioblastoma multiforme at the corpus callosum with spinal leptomeningeal metastasis
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Abstract
Glioblastoma multiforme (GBM) often occurs in the supratentorial white matter including corpus callosum. However, spinal leptomeningeal metastasis in cases of supratentorial GBM has been reported to be rare and there is usually a long interval between the cerebral lesion and the spinal seeding. We report here a case of GBM at the corpus callosum and other parts of the brain with simultaneous manifestation of spinal leptomeningeal seeding. The patient exhibited an abnormal motor behavior of the left hand as mirror movement when the right hand was performing a unimanual task (diagonistic dyspraxia) which is a sign of lesion of the posterior part and splenium of the corpus callosum. There were also signs of peripheral nerve or nerve root involvement suggestive of spinal metastasis without any sensory symptoms. He died 3 months after the onset of the symptoms confirming the poor prognosis and short survival time in cases with spinal leptomeningeal metastasis reported previously. The cerebral GBM with spinal seeding was disclosed at autopsy. © 2010 Elsevier B.V. All rights reserved.