Publication:
Efficacy and adverse events of laparoscopic gastrostomy placement in children: results of a large cohort study

dc.contributor.authorJosephine Frankenen_US
dc.contributor.authorFemke A. Mauritzen_US
dc.contributor.authorNutnicha Suksamanapunen_US
dc.contributor.authorCaroline C.C. Hulskeren_US
dc.contributor.authorDavid C. van der Zeeen_US
dc.contributor.authorMaud Y.A. van Herwaarden-Lindeboomen_US
dc.contributor.otherWilhelmina Children's Hospitalen_US
dc.contributor.otherUniversity Medical Center Utrechten_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-11-23T10:43:49Z
dc.date.available2018-11-23T10:43:49Z
dc.date.issued2015-06-01en_US
dc.description.abstract© 2014, Springer Science+Business Media New York. Introduction: A gastrostomy placement is frequently performed in pediatric patients who require long-term enteral tube feeding. However, data on efficacy, perioperative complications and postoperative gastroesophageal reflux (GER) after laparoscopic gastrostomy (LAG) placement is limited. The aim of this study is to evaluate long-term efficacy and adverse events after LAG in a large cohort and determine whether routine preoperative 24-h pH monitoring should be used to predict postoperative GER. Method: A retrospective observational cohort study was performed including 300 patients (75 % neurologically impaired) that underwent LAG. Results: After a median follow-up of 2.63 years, feeding was successful in 95.9 % of patients. Weight-for-length z-scores significantly increased (p < 0.0005). Major complications were seen in only 6 patients (2.0 %), but minor complications occurred frequently (73.6 %). Overall incidence of GER remained unchanged after LAG. Sensitivity and specificity of preoperative pH monitoring were 17.5 and 76.9 %, respectively. Conclusion: LAG placement in pediatric patients leads to successful feeding in 96 % of patients and serious adverse events are rare. However, the minor complication rate is high. Overall incidence of GER does not increase after LAG. Preoperative 24-h pH monitoring is not a reliable tool to predict postoperative GER. This invasive investigation technique should therefore not be routinely performed.en_US
dc.identifier.citationSurgical Endoscopy. Vol.29, No.6 (2015), 1545-1552en_US
dc.identifier.doi10.1007/s00464-014-3839-5en_US
dc.identifier.issn14322218en_US
dc.identifier.issn09302794en_US
dc.identifier.other2-s2.0-84928920000en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/36423
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84928920000&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleEfficacy and adverse events of laparoscopic gastrostomy placement in children: results of a large cohort studyen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84928920000&origin=inwarden_US

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