Publication: Prediction of massive transfusion in trauma patients in the surgical intensive care units (THAI-SICU study)
Issued Date
2019-08-01
Resource Type
ISSN
10081275
Other identifier(s)
2-s2.0-85067517138
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Chinese Journal of Traumatology - English Edition. Vol.22, No.4 (2019), 219-222
Suggested Citation
Osaree Akaraborworn, O. Chaiwat, Sunisa Chatmongkolchart, Chanatthee Kitsiripant, Kaweesak Chittawatanarat, Sunthiti Morakul, Thammasak Thawitsri, P. Wacharasint, Sujaree Poopipatpab, Waraporn Chau-In, Chaiyapruk Kusumaphanyo Prediction of massive transfusion in trauma patients in the surgical intensive care units (THAI-SICU study). Chinese Journal of Traumatology - English Edition. Vol.22, No.4 (2019), 219-222. doi:10.1016/j.cjtee.2019.04.004 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/51520
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Prediction of massive transfusion in trauma patients in the surgical intensive care units (THAI-SICU study)
Other Contributor(s)
Chulalongkorn University
Faculty of Medicine, Prince of Songkia University
Khon Kaen University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Faculty of Medicine, Siriraj Hospital, Mahidol University
Phramongkutklao College of Medicine
Prince of Songkla University
Chiang Mai University
Srinakharinwirot University
Navamindradhiraj University
Faculty of Medicine, Prince of Songkia University
Khon Kaen University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Faculty of Medicine, Siriraj Hospital, Mahidol University
Phramongkutklao College of Medicine
Prince of Songkla University
Chiang Mai University
Srinakharinwirot University
Navamindradhiraj University
Abstract
© 2019 Chinese Medical Association Purpose: After damage control surgery, trauma patients are transferred to intensive care units to restore the physiology. During this period, massive transfusion might be required for ongoing bleeding and coagulopathy. This research aimed to identify predictors of massive blood transfusion in the surgical intensive care units (SICUs). Methods: This is an analysis of the THAI-SICU study which was a prospective cohort that was done in the 9-university-based SICUs in Thailand. The study included only patients admitted due to trauma mechanisms. Massive transfusion was defined as received ≥10 units of packed red blood cells on the first day of admission. Patient characteristics and physiologic data were analyzed to identify the potential factors. A multivariable regression was then performed to identify the significant model. Results: Three hundred and seventy patients were enrolled. Sixteen patients (5%) received massive transfusion in the SICUs. The factors that significantly predicted massive transfusion were an initial sequential organ failure assessment (SOFA) ≥9 (risk difference (RD) 0.13, 95% confidence interval (CI): 0.03–0.22, p = 0.01); intra-operative blood loss ≥ 4900 mL (RD 0.33, 95% CI: 0.04–0.62, p = 0.02) and intra-operative blood transfusion ≥ 10 units (RD 0.45, 95% CI: 0.06 to 0.84, p = 0.02). The probability to have massive transfusion was 0.976 in patients who had these 3 factors. Conclusion: Massive blood transfusion in the SICUs occurred in 5%. An initial SOFA ≥9, intra-operative blood loss ≥4900 mL, and intra-operative blood transfusion ≥10 units were the significant factors to predict massive transfusion in the SICUs.