Publication: Incidence and risk factors of perioperative stroke in siriraj Hospital
Issued Date
2012-09-01
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ISSN
01252208
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2-s2.0-84870377920
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.95, No.9 (2012), 1167-1172
Suggested Citation
Pachara Leemingsawat, Suneerat Kongsayreepong, Chulaluk Komoltri, Naraporn Prayoonwiwat, Yongchai Nilanont Incidence and risk factors of perioperative stroke in siriraj Hospital. Journal of the Medical Association of Thailand. Vol.95, No.9 (2012), 1167-1172. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14645
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Title
Incidence and risk factors of perioperative stroke in siriraj Hospital
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Abstract
Background: Data concerning perioperative stroke incidence and risk factors are lacking in Thailand. Objective: To study incidence and risk factors ofperioperative stroke in Siriraj Hospital, Bangkok, Thailand. Material and Method: The authors conducted a nested case-control study between July 2007 and June 2010. Consecutive perioperative stroke cases were compared with age-matched controls that had undergone surgery without having a stroke at a 1:4 ratio. Patients'characteristics, co-morbidities, clinical manifestation, stroke subtypes, duration, and types of surgery were collected. Multiple logistic regression analysis was performed to identify factors associated with a stroke during perioperative period. Results: Sixty-six patients with perioperative stroke from 99,283 that underwent surgery were included. This resulted in an incidence of 66.5/100,000. Men comprised 65.2%. Mean age of stroke patients was 66.6-years-old. Age-match controls included 264 consecutive patients who underwent surgery without having a stroke. A multivariate analysis showed that male sex (adjusted OR3.1,p = 0.003), surgical types: open heart surgery (adjusted OR 54.3, p < 0.0001), vascular surgery (adjusted OR 20.6, p < 0.0001) andendovascularprocedure (adjusted OR 15.4, p < 0.0001), emergency surgery (adjusted OR 8.3, p < 0.0001), the presence of diabetes mellitus (adjusted OR 2.6, p = 0.018), chronic kidney disease (adjusted OR 2.6, p = 0.027), and coronary artery disease (adjusted OR 0.4, p = 0.039) were associated with perioperative stroke. Conclusion: Incidence ofperioperative stroke was higher than a previous report. Male, type ofsurgery, emergency operation, diabetes mellitus, and chronic kidney disease were risk factors ofperioperative stroke.