Publication:
Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process

Issued Date

2002-04-01

Resource Type

Article

ISSN

00404039

DOI

10.1016/S0040-4039(02)00329-5

Other identifier(s)

2-s2.0-0036532427

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tetrahedron Letters. Vol.43, No.14 (2002), 2601-2603

Suggested Citation

Ronald Grigg, Tossapol Khamnaen, Shuleewan Rajviroongit, Visuvanathar Sridharan Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process. Tetrahedron Letters. Vol.43, No.14 (2002), 2601-2603. doi:10.1016/S0040-4039(02)00329-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20072

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Title

Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process

Author(s)

Ronald Grigg
 Tossapol Khamnaen
 Shuleewan Rajviroongit
 Visuvanathar Sridharan

Other Contributor(s)

University of Leeds
 Mahidol University

Abstract

A novel palladium-catalysed three-component cascade process involving 2-iodobenzoyl chloride or methyl 2-iodobenzoate, allene and primary aliphatic or aromatic amines furnishes N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones in good yield. © 2002 Elsevier Science Ltd. All rights reserved.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/20072

Collections

Scopus 2001-2005