Publication: Histopathological alterations in the edible snail, Babylonia areolata (spotted babylon), in acute and subchronic cadmium poisoning
Issued Date
2005-04-25
Resource Type
ISSN
15204081
Other identifier(s)
2-s2.0-17044372437
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Environmental Toxicology. Vol.20, No.2 (2005), 142-149
Suggested Citation
P. Tanhan, P. Sretarugsa, P. Pokethitiyook, M. Kruatrachue, E. S. Upatham Histopathological alterations in the edible snail, Babylonia areolata (spotted babylon), in acute and subchronic cadmium poisoning. Environmental Toxicology. Vol.20, No.2 (2005), 142-149. doi:10.1002/tox.20088 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16518
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Histopathological alterations in the edible snail, Babylonia areolata (spotted babylon), in acute and subchronic cadmium poisoning
Other Contributor(s)
Abstract
Histopathological alterations in 6- to 8-month-old juvenile spotted babylon, Babylonia areolata, from acute and subchronic cadmium exposure were studied by light microscopy. The 96-h LC50 value of cadmium for B. areolata was found to be 3.35 mg/L, and the maximum acceptable toxicant concentration (MATC) was 1.6 mg/L. Snails were exposed to 3.35 and 0.08 mg/L (5% of MATC) of cadmium for 96 h and 90 days, respectively. After exposure the gill, the organs of the digestive system (proboscis, esophagus, stomach, digestive gland, and rectum), and the foot were analyzed for cadmium accumulation. The results showed that most digestive organs had a high affinity for cadmium. The main target organ was the stomach, which could accumulate on average 1192.18 μg/g dry weight of cadmium. Cadmium was shown to accumulate to a lesser extent in the digestive gland, gill, rectum, esophagus, proboscis, and foot. Histopathological alterations were observed in the gill and digestive organs (proboscis, esophagus, stomach, and rectum). The study showed that the stomach and gill were the primary target organs of both acute and subchronic exposure. Gill alterations included increased size of mucous vacuoles, reduced length of cilia, dilation and pyknosis of nuclei, thickening of basal lamina, and accumulation of hemocytes. The epithelial lining of the digestive tract showed similar alterations such as increased size of mucous vacuoles, reduced length of cilia, and dilation of nuclei. In addition, fragmentation of the muscle sheath was observed. © 2005 Wiley Periodicals, Inc.