Publication: Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01
2
Issued Date
2008-10-01
Resource Type
ISSN
00319422
Other identifier(s)
2-s2.0-56949101878
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Mahidol University
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SCOPUS
Bibliographic Citation
Phytochemistry. Vol.69, No.14 (2008), 2621-2626
Suggested Citation
Chairut Kasettrathat, Nattaya Ngamrojanavanich, Suthep Wiyakrutta, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01. Phytochemistry. Vol.69, No.14 (2008), 2621-2626. doi:10.1016/j.phytochem.2008.08.005 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/18693
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Title
Cytotoxic and antiplasmodial substances from marine-derived fungi, Nodulisporium sp. and CRI247-01
Abstract
Nodulisporacid A (1) was isolated from a marine-derived fungus Nodulisporium sp. CRIF1, while vermelhotin (5) was obtained from an unidentified fungus CRI247-01 (a member of the Order Pleosporales). Both 1 and 5 occurred as equilibrium E/Z mixtures. Ester derivatives (2 and 3) and vermelhotin (5) showed cytotoxic activity against eleven cancer cell lines. Nodulisporacid A (1) and vermelhotin (5) exhibited moderate antiplasmodial activity. © 2008 Elsevier Ltd. All rights reserved.