Publication: Prolonged oral etoposide for advanced uterine leiomyosarcoma with pulmonary metastases: Case report
Issued Date
1997-04-08
Resource Type
ISSN
03922936
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2-s2.0-0030897246
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Mahidol University
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SCOPUS
Bibliographic Citation
European Journal of Gynaecological Oncology. Vol.18, No.2 (1997), 97-100
Suggested Citation
W. Termrungruanglert, A. P. Kudelka, S. Piamsomboon, C. L. Edwards, C. Tornos, J. J. Kavanagh Prolonged oral etoposide for advanced uterine leiomyosarcoma with pulmonary metastases: Case report. European Journal of Gynaecological Oncology. Vol.18, No.2 (1997), 97-100. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18144
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Title
Prolonged oral etoposide for advanced uterine leiomyosarcoma with pulmonary metastases: Case report
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Abstract
A patient who had a high grade uterine leiomyosarcoma with intraabdominal and pulmonary metastases at the time of diagnosis underwent supracervical hysterectomy, bilateral salpingo-oophorectomy and tumor reductive surgery. Induction chemotherapy achieved a partial response with small amount of residual disease. On achieving a plateau in the response to her induction chemotherapy, she was switched to prolonged oral etoposide at a dose of 50 mg/m2/day 21 days with a 7-day rest period between cycles. Follow up imaging revealed stable disease with a slight decrease in the size of the paraaortic lymphnodes. Prolonged oral etoposide may be considered in patients with advanced high grade leiomyosarcoma of the uterus.