Publication: Thrombosis: A major contributor to global disease burden: ISTH steering committee for world thrombosis day the members of the ISTH steering committee for World Thrombosis Day
Issued Date
2014-01-01
Resource Type
ISSN
18792472
00493848
00493848
Other identifier(s)
2-s2.0-84927667516
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Mahidol University
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SCOPUS
Bibliographic Citation
Thrombosis Research. Vol.134, No.5 (2014), 931-938
Suggested Citation
G. E. Raskob, P. Angchaisuksiri, A. N. Blanco, H. Buller, A. Gallus, B. J. Hunt, E. M. Hylek, A. Kakkar, S. V. Konstantinides, M. McCumber, Y. Ozaki, A. Wendelboe, J. I. Weitz Thrombosis: A major contributor to global disease burden: ISTH steering committee for world thrombosis day the members of the ISTH steering committee for World Thrombosis Day. Thrombosis Research. Vol.134, No.5 (2014), 931-938. doi:10.1016/j.thromres.2014.08.014 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/34846
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Title
Thrombosis: A major contributor to global disease burden: ISTH steering committee for world thrombosis day the members of the ISTH steering committee for World Thrombosis Day
Other Contributor(s)
University of Oklahoma Health Sciences Center
Mahidol University
Academia Nacional de Medicina de Buenos Aires
Academic Medical Centre, University of Amsterdam
Flinders Medical Centre
NHS Foundation Trust
Boston University School of Medicine
Thrombosis Research Institute
Johannes Gutenberg Universitat Mainz
University of Yamanashi
Thrombosis & Atherosclerosis Research Institute
Mahidol University
Academia Nacional de Medicina de Buenos Aires
Academic Medical Centre, University of Amsterdam
Flinders Medical Centre
NHS Foundation Trust
Boston University School of Medicine
Thrombosis Research Institute
Johannes Gutenberg Universitat Mainz
University of Yamanashi
Thrombosis & Atherosclerosis Research Institute
Abstract
© 2014 The Authors. Thrombosisisacommon pathology underlying ischemic heart disease, ischemic stroke, and venous thromboem-bolism (VTE). The Global Burden of Disease Study 2010 (GBD 2010) documented that ischemic heart disease and stroke collectively caused one in four deaths worldwide. GBD 2010 did not report data for VTE as a cause of death and disability. Weperformed asystematic review of the literature on the global disease burden due toVTEinlow, middle and high income countries. Studies from Western Europe, North America, Australia, and Southern Latin America (Argentina) yielded consistent results with annual incidences ranging from 0.75 to 2.69 per 1,000 individuals in the population. The incidence increased to between 2 and 7 per 1,000 among those 70 years of age or more. Although the incidence is lower in individuals of Chinese and Korean ethnicity, their disease burden is not low because of population aging. VTE associated with hospitalization was the leading cause of disability-adjusted-life-years (DALYs) lost in low and middle income countries, and second in high income countries, responsible for more DALYs lost than nosocomial pneumonia, catheter-related blood stream infections, and adverse drug events. VTE causes a major burden of disease across low, middle, and high income countries. More detailed data on the global burden of VTE should be obtained to inform policy and resource allocation in health systems, and to evaluate if improved utilization of preventive measures will reduce the burden.