Publication: A rare association of α<sup>0</sup>-thalassemia (--<sup>SEA</sup>) and an initiation codon mutation (ATG→A-G) of the α2 gene causes Hb H disease in Thailand
| dc.contributor.author | Vip Viprakasit | en_US |
| dc.contributor.author | Worrawut Chinchang | en_US |
| dc.contributor.author | Waraporn Glomglao | en_US |
| dc.contributor.author | Voravarn S. Tanphaichitr | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-06-21T08:08:30Z | |
| dc.date.available | 2018-06-21T08:08:30Z | |
| dc.date.issued | 2005-08-16 | en_US |
| dc.description.abstract | Several rare and hitherto unidentified non deletional α-thalassemias (αTα or ααT) have been reported from Thailand within the past few years. Interactions of these determinants with α0-thalassemia (thal) (--/), which is highly prevalent in this region, give rise to various genotypes (--/ αTα or --/ααT) underlying Hb H disease. We report herein the interaction of a rare initiation codon mutation of the α2 gene and α0-thal in a Thal boy with Hb H disease. This finding highlights a wide variety of molecular pathology of the α-globin genes underlying α-thal syndrome in Southeast Asia. Copyright © 2005 Taylor & Francis, Inc. | en_US |
| dc.identifier.citation | Hemoglobin. Vol.29, No.3 (2005), 235-240 | en_US |
| dc.identifier.doi | 10.1081/HEM-200066339 | en_US |
| dc.identifier.issn | 03630269 | en_US |
| dc.identifier.other | 2-s2.0-23244456639 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/16305 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23244456639&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Medicine | en_US |
| dc.title | A rare association of α<sup>0</sup>-thalassemia (--<sup>SEA</sup>) and an initiation codon mutation (ATG→A-G) of the α2 gene causes Hb H disease in Thailand | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23244456639&origin=inward | en_US |