Publication: Parasites and asthma
Issued Date
2017-09-01
Resource Type
ISSN
14321955
09320113
09320113
Other identifier(s)
2-s2.0-85022009125
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Parasitology Research. Vol.116, No.9 (2017), 2373-2383
Suggested Citation
Lin Wuhao, Chen Ran, He Xujin, Wu Zhongdao, Paron Dekumyoy, Lv Zhiyue Parasites and asthma. Parasitology Research. Vol.116, No.9 (2017), 2373-2383. doi:10.1007/s00436-017-5548-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/41394
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Title
Parasites and asthma
Author(s)
Abstract
© 2017, Springer-Verlag GmbH Germany. Nowadays, many studies have found low morbidity of asthma in epidemic areas of parasitic diseases, as shown by the hygiene hypothesis. It is obvious that some parasite infections can prevent asthma and studies have been carried out to clarify the mechanism of the preventive effect and search for the future asthmatic therapies. Previous findings have indicated that this mechanism may be related to the immune response switching from Th1 to Th2 and important cells induced by parasites, including the regulatory T cells, regulatory B cells, dendrite cells, and alternatively activated macrophages. Cytokine IL-10 also plays a nonredundant role in protection against allergic airway inflammation in asthma. This review focuses on the relationship between parasites and asthma, and the potential protection mechanism involved.