Publication: Prevalence of Helicobacter in Laboratory Mice in Thailand
Accepted Date
2013-10-07
Issued Date
2014
Copyright Date
2014
Resource Type
Language
eng
Rights
Mahidol University
Rights Holder(s)
Japanese association for Laboratory animal science
Bibliographic Citation
Experimental Animals. Vol. 63, No. 2 (2014),169–173
Suggested Citation
Mathurot Duangchanchot, Rapee Inpunkaew., Pravate Thongsiri, Nobuhito Hayashimoto, Nobuhiro Gemma, Masaru Nikaido, Masayoshi Takahashi, Kanchana Kengkoom Prevalence of Helicobacter in Laboratory Mice in Thailand. Experimental Animals. Vol. 63, No. 2 (2014),169–173. doi:10.1538/expanim.63.169 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/22820
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Title
Prevalence of Helicobacter in Laboratory Mice in Thailand
Abstract
Prevalence of Helicobacter is mostly unknown in laboratory animals in Thailand. The 221
mice feces/cecum from 8 universities, 2 pharmaceutical companies and 3 research institutions in
Thailand were surveyed for the prevalence and distribution of Helicobacter species by using the
Electrochemical DNA chip. Helicobacter were detected 23/46 samples in Specific Pathogen Free
(SPF) and 168/175 in conventional condition. Prevalence of Helicobacter were 98%, 96%, 92% and
78% in South (n=40), Northeast (n=40), North (n=25) and Central area (n=116), respectively. Only
Central area holds SPF facility resulting in Helicobacter prevalence that seems to be lower than other
areas. Three species of Helicobacter were detected in feces/cecum samples by sequence analysis:
H. rodentium (67.0%, 148 samples), Helicobacter sp. MIT 01-6451 (15.4%, 34 samples), and
unidentified Helicobacter species (14.1%, 9 samples). The results suggested that H. rodentium is
the most common species of Helicobacter in laboratory mice in Thailand.