Publication:
Antimycobacterial dihydronaphthalenone from the endophytic fungus Nodulisporium sp. of Antidesma ghaesembilla

Issued Date

2015-10-01

Resource Type

Article

ISSN

18767486
18743900

DOI

10.1016/j.phytol.2015.08.001

Other identifier(s)

2-s2.0-84939192827

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Phytochemistry Letters. Vol.13, (2015), 375-378

Suggested Citation

Samran Prabpai, Suthep Wiyakrutta, Nongluksna Sriubolmas, Palangpon Kongsaeree Antimycobacterial dihydronaphthalenone from the endophytic fungus Nodulisporium sp. of Antidesma ghaesembilla. Phytochemistry Letters. Vol.13, (2015), 375-378. doi:10.1016/j.phytol.2015.08.001 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/35087

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Title

Antimycobacterial dihydronaphthalenone from the endophytic fungus Nodulisporium sp. of Antidesma ghaesembilla

Author(s)

Samran Prabpai
 Suthep Wiyakrutta
 Nongluksna Sriubolmas
 Palangpon Kongsaeree

Other Contributor(s)

Mahidol University
 Chulalongkorn University

Abstract

© 2015 Elsevier Ltd. Abstract Two new dihydronaphthalenones (1, 2) with four known compounds (3-6) were isolated as secondary metabolites of the endophytic fungus Nodulisporium sp. from Antidesma ghaesembilla. Their chemical structures were established based on 1D and 2D NMR spectroscopic data and HR-ESI-MS analyses. The relative configuration of 2 was confirmed by single crystal X-ray crystallographic analysis. A new isofuranonaphthalenone 2 displayed antimycobacterial and antimalarial activities with IC<inf>50</inf> values of 3.125 and 11.3 μg/mL, respectively.

Keyword(s)

Agricultural and Biological Sciences
 Biochemistry, Genetics and Molecular Biology

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URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/35087

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