Publication: Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians
Issued Date
2012-03-01
Resource Type
ISSN
13652230
03076938
03076938
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2-s2.0-84857368883
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Mahidol University
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SCOPUS
Bibliographic Citation
Clinical and Experimental Dermatology. Vol.37, No.2 (2012), 149-152
Suggested Citation
S. Kanokrungsee, N. Rajatanavin, S. Rutnin, V. Vachiramon Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians. Clinical and Experimental Dermatology. Vol.37, No.2 (2012), 149-152. doi:10.1111/j.1365-2230.2011.04197.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/14912
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Title
Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians
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Abstract
Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma. To date, there have been no data published about the efficacy of a twice-weekly regimen of narrowband ultraviolet B (NB-UVB) for the treatment of hypopigmented MF. We retrospectively reviewed 11 patients with hypopigmented MF who were treated with NB-UVB twice weekly between 2001 and 2010. Of the 11 patients, 7 achieved a complete response with a mean of 40 treatments; the remaining 4 patients had a partial response. Upon discontinuation of treatment, three patients had clinical relapse after complete remission. Median time to relapse was 10 months. A twice-weekly regimen of NB-UVB is an effective treatment for hypopigmented MF with minimal side-effects. However, the relapse rate is high, and unfortunately, no clinical or histological features can predict the relapse of the disease. © The Author(s). CED © 2012 British Association of Dermatologists.