Publication: Encapsulation of α-tocopherol in protein-based delivery particles
Issued Date
2009-10-01
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ISSN
09639969
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2-s2.0-67651003288
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Mahidol University
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SCOPUS
Bibliographic Citation
Food Research International. Vol.42, No.8 (2009), 909-914
Suggested Citation
W. Somchue, W. Sermsri, J. Shiowatana, A. Siripinyanond Encapsulation of α-tocopherol in protein-based delivery particles. Food Research International. Vol.42, No.8 (2009), 909-914. doi:10.1016/j.foodres.2009.04.021 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26970
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Title
Encapsulation of α-tocopherol in protein-based delivery particles
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Abstract
Two types of proteins, including β-lactoglobulin (BLG) and hen egg white protein (HEW), were examined for their ability to encapsulate α-tocopherol (α-TOC) after salt-induced gelation of the proteins. Parameters affecting encapsulation efficiency were investigated including the type of salt, as well as concentrations of salt, protein, and α-TOC. Concentrations of protein and α-TOC revealed to have an influence on encapsulation efficiency. The optimum preparation condition of BLG-encapsulated α-TOC was as follows: BLG of 0.5% (w/v); α-TOC of 100 mM; and CaCl2of 25 mM. The optimum preparation condition of HEW-encapsulated α-TOC was as follows: HEW of 4.0% (w/v); α-TOC of 50 mM; and ZnCl2of 25 mM. With the selected preparation conditions, encapsulation efficiency by BLG aggregates was approx. 20% and that by HEW was approx. 32%. From the in vitro estimation, the release of α-TOC was nearly 100% in simulated gastric condition. Alginate was therefore used for coating of these encapsulated particles to prolong the release of α-TOC till simulated intestinal condition. The α-TOC of approx. 55% and 38% were retained and released in the simulated intestinal condition from BLG- and HEW-encapsulated particles, respectively. © 2009 Elsevier Ltd. All rights reserved.