Publication: Iron status following trauma, excluding burns
1
Issued Date
1996-07-22
Resource Type
ISSN
00071323
Other identifier(s)
2-s2.0-8944226113
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Mahidol University
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SCOPUS
Bibliographic Citation
British Journal of Surgery. Vol.83, No.7 (1996), 982-985
Suggested Citation
D. S. Walsh, K. Pattanapanyasat, P. Lamchiagdhase, P. Siritongtaworn, P. Thavichaigarn, N. Jiarakul, C. Chuntrasakul, C. Komoltri, C. Dheeradhada, F. C. Pearce, W. P. Wiesmann, H. K. Webster Iron status following trauma, excluding burns. British Journal of Surgery. Vol.83, No.7 (1996), 982-985. doi:10.1002/bjs.1800830731 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17724
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Title
Iron status following trauma, excluding burns
Abstract
Serum concentration of iron, transferrin saturation and total iron binding capacity (TIBC) were measured on days 1, 2, 3, 5, 7, 10 and 13 in 36 Thai patients with trauma (burns excluded) to determine temporal changes in iron metabolism. Throughout the study profound hypoferraemia was observed in association with decreased transferrin saturation. TIBC, in contrast, did not differ significantly from that in controls. These findings confirm previous reports which describe altered iron metabolism in association with an adverse event, a response known as 'stress hypoferraemia', and extends these observations to non-burned patients with trauma. The degree of hypoferraemia in patients in this study was not related to sepsis, Injury Severity Score, volume of blood transfused or surgery, suggesting that hypoferraemia following trauma is an independent event. The recognition of rapid and prolonged iron sequestration provides insight into the clinical condition of patients with trauma.