Publication: Synthesis of calcium phosphate composite organogels by using castor oil and sorbitan monopalmitate based for dentine occlusion material
Issued Date
2019-09-30
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ISSN
1757899X
17578981
17578981
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2-s2.0-85074763554
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Mahidol University
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SCOPUS
Bibliographic Citation
IOP Conference Series: Materials Science and Engineering. Vol.625, No.1 (2019)
Suggested Citation
J. Waiyawat, K. Akkarachaneeyakorn, P. Changpongpan, M. Kongsema, C. Teanchai, O. Chienthavorn Synthesis of calcium phosphate composite organogels by using castor oil and sorbitan monopalmitate based for dentine occlusion material. IOP Conference Series: Materials Science and Engineering. Vol.625, No.1 (2019). doi:10.1088/1757-899X/625/1/012024 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/50835
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Title
Synthesis of calcium phosphate composite organogels by using castor oil and sorbitan monopalmitate based for dentine occlusion material
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Abstract
© Published under licence by IOP Publishing Ltd. Calcium phosphate composite organogel was synthesized from a mixture of sorbitan monopalmitate as emulsifier and castor oil as oil phase at 60 °C to establish emulsion system with calcium chloride and di-sodium hydrogen phosphate aqueous solution as water phase. The heated mixture was cooled at room temperature to form organogel. The prepared organogels were investigated by thermogravimetric analysis (TGA), scanning electron microscope (SEM), transmission electron microscope (TEM) and cytotoxicity test. The prepared organogels of 4:3 and 1:1 in oil/water content ratio were white and gritty in nature, which resulted in calcium phosphate nanoparticles with spherical shape of 1.3 to 1.9 μm and 1.2 to 2.3 μm, respectively. They were able to successfully occlude into dentine tubules within 1 day. In addition, the prepared organogels were found to have acceptable toxicity level for daily human use with high concentration up to 1600 μg/ml. Hence, these organogels showed the promising results to be developed as an effective dentine occlusion material in relieving of dentin hypersensitivity.