Publication: Health related quality of life impact from rotavirus diarrhea on children and their family caregivers in Thailand
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Issued Date
2018-03-04
Resource Type
ISSN
17448379
14737167
14737167
Other identifier(s)
2-s2.0-85030704789
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Mahidol University
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SCOPUS
Bibliographic Citation
Expert Review of Pharmacoeconomics and Outcomes Research. Vol.18, No.2 (2018), 215-222
Suggested Citation
Onwipa Rochanathimoke, Arthorn Riewpaiboon, Maarten J. Postma, Wirawan Thinyounyong, Montarat Thavorncharoensap Health related quality of life impact from rotavirus diarrhea on children and their family caregivers in Thailand. Expert Review of Pharmacoeconomics and Outcomes Research. Vol.18, No.2 (2018), 215-222. doi:10.1080/14737167.2018.1386561 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46837
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Title
Health related quality of life impact from rotavirus diarrhea on children and their family caregivers in Thailand
Abstract
© 2017 Informa UK Limited, trading as Taylor & Francis Group. Background: Rotavirus diarrhea is a major health problem among young children worldwide with potential negative impacts on health-related quality of life (HRQoL). This study assessed the impact of rotavirus diarrhea on HRQoL of children and their caregivers. Methods: We performed a cross-sectional study among 460 hospitalized children with diarrhea aged under 5 years and their family caregivers at three hospitals in Phetchabun province, Thailand during May 2013 and February 2014. The severity of diarrhea was assessed using the Vesikari severity scoring system while the HRQoL was assessed using the EQ-5D-3L. Results: The mean EQ-5D utility of children with all-causes diarrhea was 0.604. The utility of the rotavirus diarrhea group was significantly lower than that of the non-rotavirus diarrhea group (0.593 vs. 0.612; p-value = 0.040). The family caregiver’s utility was 0.964 at baseline and significantly decreased to 0.620 (p-value = 0.041) when their children were hospitalized with diarrhea. In multiple regression analyses, severity but not rotavirus infection had significant negative impacts on the utility of both the children and their caregivers. Conclusion: Diarrhea, either caused by rotavirus or non-rotavirus infection, resulted in substantial negative impacts on the quality of life of both the children and their caregivers.