Publication: The effect of Tinospora crispa on serum glucose and insulin levels in patients with type 2 diabetes mellitus
Issued Date
2012-01-03
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ISSN
11107251
11107243
11107243
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2-s2.0-84855183621
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Biomedicine and Biotechnology. Vol.2012, (2012)
Suggested Citation
Theerawut Klangjareonchai, Chulaporn Roongpisuthipong The effect of Tinospora crispa on serum glucose and insulin levels in patients with type 2 diabetes mellitus. Journal of Biomedicine and Biotechnology. Vol.2012, (2012). doi:10.1155/2012/808762 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/13827
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Title
The effect of Tinospora crispa on serum glucose and insulin levels in patients with type 2 diabetes mellitus
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Abstract
Objective. To determine the effects of Tinospora crispa on serum glucose and insulin levels in healthy subjects and patients with type 2 diabetes mellitus. Method. Serum from 10 healthy subjects and 10 diabetic participants, who had fasted overnight, were obtained every 30-60 minutes during the 3 hours of continued fasting and during the 3 hours after ingestion of 75g of glucose with or without ingestion of 125 or 250g of Tinospora crispa dry powder capsule. Glucose and Insulin levels were analyzed and the areas under the curve for mean serum glucose and insulin levels were calculated. Result. The areas under the curve of mean serum glucose and insulin levels in both healthy and diabetic participants were not significantly different between with or without Tinospora crispa dry powder capsule. In diabetic participants the area under the curve of glucose was slightly lesser when 250mg of Tinospora crispa was ingested, but not reaching statistical significance (478 and 444mg min/ml, resp., P = 0.57). Conclusion. The results suggest that Tinospora crispa ingestion cannot affect serum glucose and insulin levels in healthy subjects or patients with type 2 diabetes mellitus. Copyright © 2012 Theerawut Klangjareonchai and Chulaporn Roongpisuthipong.