Publication:
Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion for treatment of septicaemic melioidosis

Issued Date

2005-11-01

Resource Type

Article

ISSN

09248579

DOI

10.1016/j.ijantimicag.2005.07.016

Other identifier(s)

2-s2.0-26944448584

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Antimicrobial Agents. Vol.26, No.5 (2005), 403-407

Suggested Citation

Cheardchai Soontornpas, Sumarn Saraya, Malyn Chulasiri, Busba Chindavijak, Piroon Mootsikapun Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion for treatment of septicaemic melioidosis. International Journal of Antimicrobial Agents. Vol.26, No.5 (2005), 403-407. doi:10.1016/j.ijantimicag.2005.07.016 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/16542

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Title

Time-kill curves as a tool for targeting ceftazidime serum concentration during continuous infusion for treatment of septicaemic melioidosis

Author(s)

Cheardchai Soontornpas
 Sumarn Saraya
 Malyn Chulasiri
 Busba Chindavijak
 Piroon Mootsikapun

Other Contributor(s)

Khon Kaen University
 Mahidol University

Abstract

Melioidosis is a fatal community-acquired infection endemic in tropical areas. Ten isolates of the causative microorganism were subjected to time-kill study using a range of ceftazidime concentrations. This study demonstrated that a ceftazidime concentration of eight times the minimum inhibitory concentration yielded an optimal bactericidal effect and should be the target concentration administered by continuous infusion. © 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

Keyword(s)

Immunology and Microbiology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/16542

Collections

Scopus 2001-2005