Publication: Application of deuterated THENA for assigning the absolute configuration of chiral secondary alcohols
| dc.contributor.author | Jakapun Soponpong | en_US |
| dc.contributor.author | Kulvadee Dolsophon | en_US |
| dc.contributor.author | Chawanee Thongpanchang | en_US |
| dc.contributor.author | Anthony Linden | en_US |
| dc.contributor.author | Tienthong Thongpanchang | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | University of Zurich | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.contributor.other | Srinakharinwirot University | en_US |
| dc.date.accessioned | 2020-01-27T07:49:30Z | |
| dc.date.available | 2020-01-27T07:49:30Z | |
| dc.date.issued | 2019-02-07 | en_US |
| dc.description.abstract | © 2019 Elsevier Ltd The structure of a constrained bicyclic chiral derivatizing agent (CDA), 1,2,3,4-tetrahydro-1,4-epoxynaphthalene-1-carboxylic acid, THENA 1, was modified by replacing both exo-methylene protons with deuterium atoms. The modified CDA, THENA-d 2 2, could be used to assign the absolute configuration of chiral secondary alcohols with good reliability. Compared with THENA, the multiplicity of the methylene proton signals in the 1 H NMR spectra of THENA-d 2 derivatives is less complicated and the new CDA thus offers simpler NMR spectra for data interpretation. | en_US |
| dc.identifier.citation | Tetrahedron Letters. Vol.60, No.6 (2019), 497-500 | en_US |
| dc.identifier.doi | 10.1016/j.tetlet.2019.01.013 | en_US |
| dc.identifier.issn | 18733581 | en_US |
| dc.identifier.issn | 00404039 | en_US |
| dc.identifier.other | 2-s2.0-85059805363 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/50259 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059805363&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.title | Application of deuterated THENA for assigning the absolute configuration of chiral secondary alcohols | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059805363&origin=inward | en_US |