Publication: Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum-Addressing the Safety and Effectiveness of Vitamin A Supplementation
Issued Date
2020-03-01
Resource Type
ISSN
21565376
Other identifier(s)
2-s2.0-85081941460
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Advances in nutrition (Bethesda, Md.). Vol.11, No.2 (2020), 185-199
Suggested Citation
Daniel J. Raiten, Ian Darnton-Hill, Sherry A. Tanumihardjo, Parminder S. Suchdev, Emorn Udomkesmalee, Carolina Martinez, Dora Inés Mazariegos, Musonda Mofu, Klaus Kraemer, Homero Martinez Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum-Addressing the Safety and Effectiveness of Vitamin A Supplementation. Advances in nutrition (Bethesda, Md.). Vol.11, No.2 (2020), 185-199. doi:10.1093/advances/nmz100 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/53519
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum-Addressing the Safety and Effectiveness of Vitamin A Supplementation
Other Contributor(s)
Institute of Nutrition of Central America and Panama Guatemala
University of Wisconsin-Madison
The University of Sydney
Tufts University
National Institute of Child Health and Human Development
Mahidol University
Johns Hopkins Bloomberg School of Public Health
Emory University
Hospital Infantil de Mexico Federico Gomez
Nutrition International
Sight and Life
National Food and Nutrition Commission
University of Wisconsin-Madison
The University of Sydney
Tufts University
National Institute of Child Health and Human Development
Mahidol University
Johns Hopkins Bloomberg School of Public Health
Emory University
Hospital Infantil de Mexico Federico Gomez
Nutrition International
Sight and Life
National Food and Nutrition Commission
Abstract
Copyright © American Society for Nutrition 2019. An ongoing challenge to our ability to address the role of food and nutrition in health promotion and disease prevention is how to design and implement context-specific interventions and guidance that are safe, efficacious, and avoid unintended consequences. The integration to effective implementation (I-to-I) concept is intended to address the complexities of the global health context through engagement of the continuum of stakeholders involved in the generation, translation, and implementation of evidence to public health guidance/programs. The I-to-I approach was developed under the auspices of the Micronutrient Forum and has been previously applied to the question of safety and effectiveness of interventions to prevent and treat nutritional iron deficiency. The present article applies the I-to-I approach to questions regarding the safety and utility of large-dose vitamin A supplementation programs, and presents the authors' perspective on key aspects of the topic, including coverage of the basic and applied biology of vitamin A nutrition and assessment, clinical implications, and an overview of the extant data with regard to both the justification for and utility of available intervention strategies. The article includes some practical considerations based on specific country experiences regarding the challenges of implementing vitamin A-related programs. This is followed by an overview of some challenges associated with engagement of the enabling communities that play a critical role in the implementation of these types of public health interventions. The article concludes with suggestions for potential approaches to move this important agenda forward.