Publication: Association between celiac disease and schizophrenia: A meta-Analysis
Issued Date
2018-01-01
Resource Type
ISSN
14735687
0954691X
0954691X
Other identifier(s)
2-s2.0-85044275317
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
European Journal of Gastroenterology and Hepatology. Vol.30, No.4 (2018), 442-446
Suggested Citation
Karn Wijarnpreecha, Veeravich Jaruvongvanich, Wisit Cheungpasitporn, Patompong Ungprasert Association between celiac disease and schizophrenia: A meta-Analysis. European Journal of Gastroenterology and Hepatology. Vol.30, No.4 (2018), 442-446. doi:10.1097/MEG.0000000000001048 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/47200
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Association between celiac disease and schizophrenia: A meta-Analysis
Abstract
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved. Background/objective Recent epidemiologic studies have suggested that patients with celiac disease might be at an increased risk of schizophrenia. However, the data on this risk remain inconclusive. This meta-Analysis was conducted with the aim to summarize all available evidence. Methods A literature search was carried out using MEDLINE and Embase database from inception to June 2017. Studies that compared the risk of schizophrenia among patients with celiac disease versus individuals without celiac disease were included. Pooled odds ratio and 95% confidence interval were calculated using a random-effect, generic inverse-variance method. Results Of the 284 retrieved studies, four met our eligibility criteria and were included in the analysis. We found a higher risk of schizophrenia among patients with celiac disease compared with individuals without celiac disease with the pooled odds ratio of 2.03 (95% confidence interval: 1.45-2.86). The statistical heterogeneity of this study was insignificant (I 2 =0%). Conclusion This systematic review and meta-Analysis found a significantly higher risk of schizophrenia among patients with celiac disease.